Date: May 12, 2021
Time: 04:00 PM CET / 10:00 AM EDT
Duration: 1 hour
- Appreciation of the ethical, statistical, and regulatory issues involved in rare and pediatric disease clinical trials
- Guidance on how Bayesian approaches can use natural history data to supplement results of a one-arm study of a rare disease intervention
- Comparison of one- and two-arm approaches, again highlighting tradeoffs between the need for unbiased estimation and concomitant ethical and practical constraints
Senior Advisor, Data Science, PharmaLex
Brad is a statistical researcher, methodologist, consultant, and instructor. Prior to joining PharmaLex, he spent 27 years on the faculty of the Division of Biostatistics at the University of Minnesota School of Public Health, serving as division head for 7 of those years. He has published more than 185 papers in refereed books and journals, and has co-authored three popular textbooks on Bayesian statistical methods and their applications in spatial statistics and adaptive clinical trials. During his spare time, Brad is a health musician and bandleader, providing keyboards and vocals in a variety of venues. He is excited and proud to be a part of the PharmaLex data science and statistics team.
Senior Manager Statistics, PharmaLex
Arnaud holds a bachelor’s degree in Mathematics and a master degree in statistics and econometrics (Université Catholique de Louvain). He is a Senior Manager Statistics and Data Science at PharmaLex and has been at PharmaLex for the past 5 years. He has been primarily involved in various projects covering non-clinical, pre-clinical as well as clinical projects.